Ethanamine, 2-(1H-indazol-6-yloxy)-N,N-dimethyl- - Names and Identifiers
Ethanamine, 2-(1H-indazol-6-yloxy)-N,N-dimethyl- - Physico-chemical Properties
Ethanamine, 2-(1H-indazol-6-yloxy)-N,N-dimethyl- - Introduction
Ethanamine, 2-(1H-indazol-6-yloxy)-N,N-dimethyl-is an organic compound with the chemical formula C12H16N4O. It is a white solid with indazole and ethylamine groups. The following are some of the properties, uses, preparation and safety information about the compound:
Nature:
-Appearance: White solid
-Molecular weight: 232.28g/mol
-Melting point: 148-152°C
-Boiling point: 424.7°C
-Solubility: Can be dissolved in most organic solvents, such as alcohols and ethers
Use:
- Ethanamine, 2-(1H-indazol-6-yloxy)-N,N-dimethyl-can be used as intermediates and raw materials in the field of medicine. It has certain antiviral and anticancer activities, so it can be used as a precursor of potential antiviral and antitumor drugs in drug research and development.
Preparation Method:
- Ethanamine, 2-(1H-indazol-6-yloxy)-N,N-dimethyl-can be prepared by the following steps:
1. pyridine is added to the sodium hydroxide solution.
2. Condense 1-(2-chloromethylethyl)-1H-indazol-6-ol into pyridine at low temperature with dichloromethane as solvent.
3. stannous bromide is added as a reducing agent to give Ethanamine, 2-(1H-indazol-6-yloxy)-N,N-dimethyl-.
Safety Information:
- Ethanamine, 2-(1H-indazol-6-yloxy)-N,N-dimethyl-May be irritating to eyes, skin and respiratory tract.
-Personal protective equipment such as protective gloves, goggles and protective masks are recommended when handling this compound.
-Avoid contact with oxidants and acids to prevent fire and explosion.
-Follow chemical safety procedures during use and storage, and pay attention to a well-ventilated environment. If necessary, refer to the relevant safety data form or consult with a chemical expert.
Last Update:2024-04-09 15:17:59